Biochemical Effects of Hexabromocyclododecane (HBCD) diastereoisomers in Juvenile Rainbow trout (Onch orhynchus mykiss)

نویسندگان

  • Vince P. Palace
  • Kerri Pleskach
  • Thor Halldorson
  • Robert Danell
  • Kerry Wautier
  • Robert Evans
  • Mehran Alaee
  • Chris Marvin
  • Gregg Tomy
چکیده

Introduction Brominated flame retardants are widely used and increasingly detected in abiotic and biotic compartments globally. Tetrabromobisphenol, polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCD) are most ubiquitous. HBCD is the principle fire retardant in polystyrene foams that are used as insulation in the building industry and for upholstering furniture. Bioaccumulation of HBCD in animals and humans has caused concern regarding the potential for health effects (Zegers et al. 2006, Tomy et al. 2004). Among these potential health effects, disturbance of the thyroid axis has recently been reported (Yamada-Okabe et al. 2005).

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تاریخ انتشار 2006